Even so, if you have a severe corn allergy, you may want to avoid corn-based spirits, most especially bourbon. Gin, whiskey, brandy, and some vodkas may also use corn as.... Alcohol intolerance is due to a genetic polymorphism of the enzyme alcohol dehydrogenase, the enzyme that metabolises ingested alcohol. Alcohol intolerance. Connected to: From Wikipedia, the free encyclopedia. Medical condition. Alcohol intolerance. Other names. Alcohol intolerance can cause people to feel unpleasant symptoms after drinking alcohol, including skin flushing, nausea and vomiting, headache, and a rapid heartbeat. It's caused by the lack of an enzyme that breaks down alcohol in the body, called alcohol dehydrogenase. It's more common in Asian populations.